Product Information
MW: 8.5 kDa
Concentration: 2mg/mL
Buffer: 50mM PBS, pH7.0, 150mM NaCl
Solubility: Aqueous solutions up to 50 mg/ml
Purity: > 95% by SDS‐PAGE
Storage: Store at ‐20℃. Avoid multiple FREEZE/THAW cycles.
产品编号 | 规格 | 价格 | 货期 | |
UBM-K48C | 1mg | ¥750 | 现货 |
Product Description
Mutation of lysine 48 to cystine renders ubiquitin (Ub) unable to form poly-Ub chains via lysine 48 linkages with other Ub molecules. Ub K48C can form an E1-catalyzed active thioester at the C-terminus allowing the molecule to be transferred to the lysines of substrate proteins (monoubiquitination). Ideal for the reduction in poly-Ub chain length/conjugation rates and determining if poly-Ub chains are K48 linked.